+234 700 079 6522 Test Results

Neobona

Chromosomal abnormalities are associated with miscarriage, fetal abnormalities, and developmental and/or growth delays in the baby. Get screened. Give your baby the best chance of living a healthy life.

Confidential

Quick turnaround

Reliable accuracy

How it works

Order online

Order your test online, select, and pay for your preferred panel.

Collect your sample

Choose to have our medical team come in for home sample collection or visit a Synlab centre near you for your sample collection.

Review accurate results

Accurate and confidential results are available on your secure online Pathprovider account. You will get notified as soon as your results are available.

Get medical support

If you have any queries, please contact our 24-hour customer support centre at +234 700 7284 2273.

STATISTICS

1 in 20

Pregnancies are incorrectly classified as high risk.

1 in 10

Fetuses with down syndrome are not detected when using conventional screening (false-negative results).

1 in 700

Children born in Nigeria have Down Syndrome.

NeoBona is the new generation of screening for non-invasive prenatal diagnosis.

It detects the most common chromosomal abnormalities occurring during pregnancy by analyzing the fetal DNA present in the mother’s blood. 

NeoBona detects the most frequent chromosomal abnormalities that occur during pregnancy by studying the cell-free fetal DNA present in maternal blood.

 

 

Benefits of NeoBona

  • Accurate – Overall detection rate is higher than 99% for Down’s, Edwards, and Patau Syndrome.
  • Simple – A single blood sample from the mother is all that is needed.
  • Safe – The test is non-invasive and carries no risk to the fetus
  • Fast – Results are typically available in 10 working days.
  • Advanced – The analysis is based on cutting-edge technology from Illumina, a world leader in DNA sequencing

Why choose NeoBona?

  1. Confidence
    NeoBona offers parents assurance that chromosomal abnormalities in the fetus can be detected early during pregnancy. A non-invasive test does not carry any risk to the future baby.
  2. Professional Counseling
    Genetic counselling is recommended before a NeoBona test. NeoBona is the only prenatal test available that has the support of a team of over 1,000 medical professionals and genetics experts who work closely with your doctor.
  3. Fetal Fraction
    Unlike other prenatal tests, NeoBona specifically analyses cell-free fetal DNA through sizing technology, improving the accuracy of the result. This innovation through technology, developed by Illumina, a world leader in DNA sequencing, integrates state-of-the-art technology and know-how to offer an innovative non-invasive prenatal test.
  4. Next-generation Bioinformatics
    The innovative algorithm generates the TSCORE (Trisomy Score) using the depth of sequencing, the percentage of cell-free fetal DNA, and the quantification of total and fetal DNA fragments to obtain reliable results even at a low fetal fraction.
  1. Accuracy
    Conventional first-trimester screening consists of blood and ultrasound analysis and provides only a statistical risk index. NeoBona directly analyses cell-free DNA and so provides a greater accuracy: better detection and fewer false positives.
  2. Specificity
    Conventional first-trimester screening has a specificity of 95%. In other words, out of every 100 healthy pregnancies, five are incorrectly classified as high risk, leading to anxiety, counselling, and further testing, including prenatal diagnosis. The very high specificity of NeoBona reduces the number of false-positive results to less than 1 in 1,500 pregnancies.
  3. Sensitivity
    Conventional first-trimester screening has a sensitivity of about 90%: out of every 100 fetuses with Down syndrome (trisomy 21), ten would not be detected (false-negative results). The overall sensitivity of neoBona for Down’s, Edwards, and Patau’s syndromes is higher than 99%.

Chromosomal abnormalities detected through NeoBona:

Neobona detects the most frequent trisomies. A trisomy is caused by the presence of an additional copy of a chromosome instead of the normal two. NeoBona detects the following trisomies:

Trisomy 21 (Down's syndrome)

Children affected by this can have mild to moderate intellectual impairment, heart defects, and/or other disorders.

Trisomy 18 (Edward's syndrome)

Affected infants typically have severe malformation and mental impediments and rarely survive beyond one year of age. 

Trisomy 13 (Patau's syndrome)

Infants with Patau syndrome have severe mental impediments, can exhibit severe congenital heart malformations and other pathologies, and rarely survive beyond one year of age.

Klinefelter’s syndrome

Affects males when the normal male karyotype, 46, XY, has at least one extra X chromosome. It is characterised by small testes, low or no sperm cells, breast buds in puberty, and behavioural problems.

Turner syndrome

The absence of a single X chromosome in the female. During childhood, girls may have short stature, and in later life, they have problems with puberty and fertility.

Fetal sex is an optional extra. It is also available for twins. If the ‘fetal sex’ option is selected in twin pregnancies and the presence of the Y chromosome is detected, at least one of the fetuses is male.

Frequently Asked Questions

If you are still unsure about this test, here are some questions that we usually get asked.

Still need answers?

I am pregnant. Is NeoBona suitable for me?

NeoBona is available from 10 weeks of pregnancy. 

NeoBona can be performed in cases of assisted reproduction, including IVF, after donor eggs and sperm are used. It is suitable for twin pregnancies

NeoBona is a genetic screening test and, as such, must be prescribed by your physician.

 

How does prenatal genetic testing help you?

Peace of mind: Genetic testing answers questions you might have concerning your baby’s health.

Quality decisions: When you have these answers, you are equipped with information that helps you decide the best ways to prepare for you and your baby.

 Adequate planning and preparation: It gives you time to plan for your baby’s needs with regards to implementing the decision you have chosen and are also aware of what outcomes to expect.

Why should I consider NeoBona in my pregnancy?

Age: Babies of pregnant women who are aged 35 years and above have an increased chance of having a chromosomal abnormality.

Family history: If a member of the parent’s family or any of their children has a chromosomal abnormality, it increases the risk for current pregnancy. 

Birth defect in a previous baby: Having had a live-born baby with a birth defect or a stillborn baby—even when no one knows whether the baby had a chromosomal abnormality—increases the risk of having a baby with a chromosomal abnormality.

Miscarriages: Having had several miscarriages may increase the risk of having a baby with a chromosomal abnormality.

Chromosomal abnormality in a prospective parent – A chromosomal abnormality in one or both parents increases the risk, even if the affected parent is healthy and has no physical sign of the abnormality.

Benefits

When you get your test done with SYNLAB, you have access to our benefits.

REPORTING

Customer-centric reporting

PathProvider gives you direct access to all of your test results and reports across all your devices without having to leave your home.

Benefits of being a PathProvider registered user

  • Your profile is a secure personal space
  • Access your results any time, any day, all year round
  • Results can be checked on any smartphone, computer, or tablet
  • All your previous results are archived on your profile
  • Set your notification preferences when results are ready. Choose email or SMS.
  • Not a doctor? Switch to the popular ‘graphic view’ and get to understand your results.
  • You can share or print your results directly from your profile.
CONVENIENCE

Choose home collection.

Get complete convenience

Get your results as they become available online.

We come to you. Our at-home collection service is designed to save you time and is completely confidential and discreet.

You can choose to get your entire family tested in the comfort of your own home. Choose a day and a time that is convenient for you, and we’ll send one of our trained professionals to your door.

No more sitting in traffic. Now you can manage your health in the comfort of your own home.

CONFIDENCE

Total confidence.

Award-winning medical diagnostics

Accuracy of results, reliability, trust, and quick turnaround time.

We have had ISO 15189 international accreditation since 2006. Our vast experience in medical diagnostics ensures that we continue to set the benchmark for reliable, accurate, and quality analysis in Nigeria.

We are audited by an external body which ensures that we implement the highest ethical standards and international best practices.

SYNLAB was awarded the 'Private Laboratory Service Provider of the Year' in Nigeria award by the Nigeria Health Excellence Awards (NHEA).

Select the test that’s right for you